Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229142 | 0.74 | TSHR (0.58) | TSHRMAPK1SMN1; SMN2PGK1VCAM1 | |
| SCHEMBL6239786 | 0.73 | TSHR (0.46) | TSHRMAPK1PGK1VCAM1ALDH1A1 | |
| SCHEMBL6501572 | 0.72 | TSHR (0.48) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL15358170 | 0.70 | PDE7A (0.49) | TSHRMAPK1SMN1; SMN2PGK1GRIN2D | |
| SCHEMBL7744893 | 0.69 | TSHR (0.46) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL20610164 | 0.66 | TSHR (0.39) | TSHRMAPK1SMN1; SMN2PGK1VCAM1 | |
| SCHEMBL17824466 | 0.66 | ALDH1A1 (0.40) | TSHRMAPK1SMN1; SMN2PGK1VCAM1 | |
| SCHEMBL2777612 | 0.66 | PDE7A (0.55) | TSHRMAPK1SMN1; SMN2VCAM1ALDH1A1 | |
| SCHEMBL22557347 | 0.66 | ALDH1A1 (0.41) | TSHRMAPK1SMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL1192999 | 0.66 | MAPT (0.46) | TSHRMAPK1SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071493-A | Pesticidally active heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2018-12-21 | — | — | CN | disclosed |