Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620861 | 0.85 | SCN9A (0.44) | RBP4 | |
| SCHEMBL30624457 | 0.74 | GPR119 (0.41) | RBP4MMP13MMP3MMP9MMP1 | |
| SCHEMBL2488001 | 0.72 | RBP4 (0.44) | RBP4F2PDE4B | |
| SCHEMBL28451352 | 0.71 | TGFBR1 (0.48) | RBP4 | |
| SCHEMBL618465 | 0.71 | RBP4 (0.47) | RBP4F2PDE4B | |
| SCHEMBL618608 | 0.71 | RBP4 (0.48) | RBP4F2 | |
| SCHEMBL31670305 | 0.71 | ALOX5AP (0.47) | RBP4ALDH1A1 | |
| SCHEMBL621284 | 0.71 | ALOX5AP (0.47) | RBP4ALDH1A1 | |
| SCHEMBL621999 | 0.70 | RBP4 (0.43) | RBP4F2SMN1; SMN2 | |
| SCHEMBL4194134 | 0.69 | SMN1; SMN2 (0.45) | MMP13MMP3MMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |