Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458848 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AMEN1GAAPIK3CG | |
| SCHEMBL6234745 | 0.82 | ALDH1A1 (0.62) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL3950505 | 0.80 | PTGER4 (0.62) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL12493966 | 0.80 | SLC22A12 (0.57) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL8807187 | 0.77 | GAA (0.55) | SMN1; SMN2KMT2AMEN1GAAPIK3CG | |
| SCHEMBL30644304 | 0.77 | ALDH1A1 (0.69) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL557409 | 0.77 | ALDH1A1 (0.69) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL6687908 | 0.77 | KMT2A (0.56) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL6687911 | 0.77 | KMT2A (0.56) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL20615143 | 0.76 | CALM1 (0.58) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |