Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 5/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004610 | 0.93 | F2RL3 (0.57) | F2RL3CNR2PIM1VCPFYN | |
| SCHEMBL623847 | 0.91 | F2RL3 (0.52) | F2RL3CNR2PIM1VCPFYN | |
| SCHEMBL623578 | 0.87 | F2RL3 (0.48) | F2RL3PIM1VCPFYNEPHB4 | |
| SCHEMBL623883 | 0.86 | F2RL3 (0.52) | F2RL3PIM1VCPFYNPIM2 | |
| SCHEMBL1946067 | 0.86 | F2RL3 (0.52) | F2RL3CNR2PIM1VCPFYN | |
| SCHEMBL625205 | 0.86 | F2RL3 (0.53) | F2RL3CNR2PIM1VCPFYN | |
| SCHEMBL628029 | 0.83 | F2RL3 (0.49) | F2RL3PIM1GAAACKR3 | |
| SCHEMBL2257601 | 0.82 | F2RL3 (0.55) | F2RL3VCP | |
| SCHEMBL624030 | 0.81 | FYN (0.59) | PIM1CHRM4FYNPIM2 | |
| SCHEMBL1947246 | 0.80 | F2RL3 (0.55) | F2RL3VCPFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |