Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354861 | 0.85 | ALDH1A1 (0.73) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 | |
| SCHEMBL18617549 | 0.82 | TDP1 (0.46) | ALDH1A1HTTSMN1; SMN2DRD2DRD1 | |
| SCHEMBL3825898 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 | |
| SCHEMBL10913527 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 | |
| SCHEMBL5481438 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 | |
| SCHEMBL31175932 | 0.76 | KMT2A (0.71) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 | |
| SCHEMBL2474418 | 0.76 | ERN1 (0.57) | ALDH1A1HTTSMN1; SMN2HPGDSRC | |
| SCHEMBL249552 | 0.76 | KMT2A (0.71) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 | |
| SCHEMBL5030438 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 | |
| SCHEMBL8622754 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HTTSMN1; SMN2HPGDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017354-B1 | TRANSLUCENT WEAR RESISTANT DENTAL ENAMEL MATERIAL AND METHOD | DENTSPLY INT INC (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6391940-B1 | PHOTOPOLYMERIZABLE ACRYLATED COMPOUND | DENTSPLY RESEARCH & DEVELOPMENT CORP. | 2002-05-21 | — | — | US | disclosed |
| US-6262142-B1 | USEFUL IN MAKING ARTIFICIAL TOOTH ENAMEL, INLAYS, ONLAYS AND VENEERS | DENTSPLY RESEARCH & DEVELOPMENT | 2001-07-17 | — | — | US | disclosed |
| EP-1017354-A1 | TRANSLUCENT WEAR RESISTANT DENTAL ENAMEL MATERIAL AND METHOD | Dentsply International, Inc. (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-2000003688-A1 | TRANSLUCENT WEAR RESISTANT DENTAL ENAMEL MATERIAL AND METHOD | DENTSPLY INTERNATIONAL INC. (US) | 2000-01-27 | — | — | WO | disclosed |