Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 8/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774515 | 0.80 | HTT (0.54) | HTTKDM4ELMNASMN1; SMN2NPY1R | |
| SCHEMBL2995379 | 0.79 | BCHE (0.54) | HTTKDM4ELMNASMN1; SMN2NPY1R | |
| SCHEMBL8318400 | 0.73 | ABCB1 (0.65) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL13009614 | 0.73 | PTGER1 (0.49) | HTTKDM4ELMNASMN1; SMN2NPY1R | |
| SCHEMBL8409730 | 0.72 | HTR1A (0.60) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8318934 | 0.72 | HTR1A (0.60) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8409069 | 0.71 | ABCB1 (0.59) | KDM4ELMNAPTGER1PTGER4PTGER3 | |
| SCHEMBL3241541 | 0.71 | SLC2A1 (0.54) | HTTKDM4ELMNASMN1; SMN2NPY1R | |
| SCHEMBL2987073 | 0.71 | BCHE (0.57) | HTTKDM4ELMNASMN1; SMN2NPY1R | |
| SCHEMBL15726355 | 0.70 | PTGER1 (0.84) | PTGER1PTGER4PTGER3PTGER2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216225-B1 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-07-06 | — | — | EP | disclosed |