Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | FGB | P02675 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245050 | 0.78 | LMNA (0.49) | HTTMAPTHPGDMEN1KMT2A | |
| SCHEMBL6252888 | 0.72 | IMPDH2 (0.49) | HSD17B10HPGDMAPK1ALDH1A1DYRK1A | |
| SCHEMBL22226391 | 0.69 | ALDH1A1 (0.51) | ALOX15HSD17B10HTTMAPTHPGD | |
| SCHEMBL6752502 | 0.69 | MAPT (0.50) | ALOX15HSD17B10HTTMAPTHPGD | |
| SCHEMBL9508150 | 0.69 | CA1 (0.55) | ALOX15HSD17B10HTTMAPTHPGD | |
| SCHEMBL69897 | 0.69 | CA1 (0.55) | ALOX15HSD17B10HTTMAPTHPGD | |
| SCHEMBL6242539 | 0.68 | CA12 (0.42) | ALOX15HSD17B10HTTMAPTHPGD | |
| SCHEMBL22226781 | 0.68 | LMNA (0.82) | ALOX15HSD17B10HTTMAPTHPGD | |
| SCHEMBL5747335 | 0.68 | ALDH1A1 (0.44) | ALOX15HSD17B10HTTMAPTHPGD | |
| SCHEMBL69025 | 0.67 | PTPN11 (0.68) | ALOX15HSD17B10HTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361873-A4 | MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1361873-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002064080-A2 | MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LCC (US) | 2002-08-22 | — | — | WO | disclosed |