Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.71 |
| ▸ | CDK4 | P11802 | 8/20 | 0.61 |
| ▸ | CDK1 | P06493 | 3/20 | 0.60 |
| ▸ | IKBKB | O14920 | 3/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243791 | 0.85 | CDK2 (0.57) | CDK2CDK4CDK1IKBKBCCNE1 | |
| SCHEMBL6244692 | 0.85 | CDK2 (0.78) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL6594955 | 0.83 | CDK2 (1.00) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4820462 | 0.81 | CDK2 (0.80) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4817036 | 0.81 | CDK2 (0.79) | CDK2CDK4CDK1IKBKBCCNE1 | |
| SCHEMBL6245840 | 0.80 | CDK2 (0.76) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4821591 | 0.80 | CDK2 (0.72) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL7978102 | 0.78 | CDK2 (0.50) | CDK2CDK4CDK1CCNE1 | |
| SCHEMBL6245628 | 0.78 | CDK2 (0.69) | CDK2CDK4CDK1CCNE1 | |
| SCHEMBL4855523 | 0.78 | CDK2 (0.83) | CDK2CDK4CDK1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362050-B1 | PYRIMIDINE DERIVATIVES FOR INHIBITION OF CELL-PROLIFERATION | ASTRAZENECA AB (SE) | 2005-02-02 | — | — | EP | claimed |