Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | KCNH3 | Q9ULD8 | 9/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240085 | 0.84 | TDP1 (0.70) | TDP1KCNH3CTSSCTSK | |
| SCHEMBL6240473 | 0.80 | TDP1 (0.61) | TDP1KCNH3CTSSCTSK | |
| SCHEMBL6237210 | 0.79 | TDP1 (0.75) | TDP1KCNH3CTSK | |
| SCHEMBL6235242 | 0.78 | CTSK (0.76) | TDP1CTSK | |
| SCHEMBL1923791 | 0.77 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL6240322 | 0.77 | CTSS (0.64) | TDP1KCNH3CTSSCTSK | |
| SCHEMBL13363711 | 0.76 | TDP1 (0.70) | TDP1KCNH3CTSK | |
| SCHEMBL6240598 | 0.75 | TDP1 (0.68) | TDP1KCNH3CTSK | |
| SCHEMBL13420924 | 0.75 | KCNH3 (0.69) | KCNH3 | |
| SCHEMBL13421020 | 0.75 | KCNH3 (0.69) | KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |