Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.67 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506226 | 0.81 | AKR1C3 (0.61) | HSD11B1MAPTALDH1A1PIM1PIM2 | |
| SCHEMBL21539509 | 0.81 | CYP1A2 (0.64) | NPC1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL6851578 | 0.81 | CYP1A2 (0.64) | NPC1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL8947502 | 0.77 | MAPT (0.61) | METAP1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10620175 | 0.77 | IGF1R (0.47) | HSD11B1NPC1MEN1MAPTPKM | |
| SCHEMBL29506225 | 0.77 | CYP1A2 (0.61) | METAP1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL10620169 | 0.77 | IGF1R (0.47) | HSD11B1NPC1MEN1MAPTPKM | |
| SCHEMBL8947501 | 0.77 | MAPT (0.61) | METAP1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29506223 | 0.76 | MAPT (0.56) | METAP1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL643539 | 0.76 | HSD11B1 (0.76) | HSD11B1IKBKBNPC1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |