Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SI | P14410 | 3/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MIF | P14174 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21539509 | 1.00 | CYP1A2 (0.64) | CYP1A2ALDH1A1HTTF3MAOB | |
| SCHEMBL2201906 | 0.89 | ALDH1A1 (0.76) | CYP1A2ALDH1A1HTTF3MAOB | |
| SCHEMBL5585178 | 0.89 | ALDH1A1 (0.76) | CYP1A2ALDH1A1HTTF3MAOB | |
| SCHEMBL30424729 | 0.85 | ALDH1A1 (0.77) | CYP1A2ALDH1A1HTTF3MAOB | |
| SCHEMBL29506226 | 0.81 | AKR1C3 (0.61) | CYP1A2ALDH1A1MAOBMAPTMAOA | |
| SCHEMBL624285 | 0.81 | HSD11B1 (0.67) | CYP1A2ALDH1A1MAOBMAPTMAOA | |
| SCHEMBL8947501 | 0.80 | MAPT (0.61) | CYP1A2ALDH1A1HTTHPGDMAPT | |
| SCHEMBL8947502 | 0.80 | MAPT (0.61) | CYP1A2ALDH1A1HTTHPGDMAPT | |
| SCHEMBL1414018 | 0.79 | ALDH1A1 (0.68) | CYP1A2ALDH1A1HTTF3MAOB | |
| SCHEMBL12272592 | 0.79 | ALDH1A1 (0.62) | CYP1A2ALDH1A1HTTF3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012087-B | Green synthetic method of alpha, alpha'-double benzylidene cycloalkanone compound | DALIAN CHEMICAL PHYSICS INST | 2015-02-04 | — | — | CN | claimed |
| CN-100497293-C | Method of preparing alpha,alpha'-di(substituted benzylidene)cyclone ultraviolet radiation absorbent | UNIV ZHEJIANG (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-101054348-A | Method of preparing alpha,alpha'-di(substituted benzylidene)cyclone ultraviolet radiation absorbent | UNIV ZHEJIANG (CN) | 2007-10-17 | — | — | CN | claimed |
| EP-4419094-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | Edison Oncology (US) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023069727-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | EDISON ONCOLOGY (US) | 2023-04-27 | — | — | WO | disclosed |
| US-11603458-B2 | Black resin composition, cured film, and black filter | ECHEM SOLUTIONS CORP. (TW) | 2023-03-14 | — | — | US | disclosed |
| CN-114326307-A | Black resin composition, cured film, and black filter | 新应材股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20220098398-A1 | BLACK RESIN COMPOSITION, CURED FILM, AND BLACK FILTER | ECHEM SOLUTIONS CORP. (TW) | 2022-03-31 | — | — | US | disclosed |
| WO-2020121653-A1 | HOLOGRAM RECORDING COMPOSITION, HOLOGRAM RECORDING MEDIUM, DIFFRACTION OPTICAL ELEMENT, AND OPTICAL DEVICE, OPTICAL COMPONENT, AND IMAGE DISPLAY DEVICE IN WHICH DIFFRACTION OPTICAL ELEMENT IS USED | ソニー株式会社 | 2020-06-18 | — | — | WO | disclosed |
| US-10576067-B2 | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof | ANKH LIFE SCIENCES LIMITED (IE) | 2020-03-03 | — | — | US | disclosed |
| US-10471049-B2 | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof | ANKH LIFE SCIENCES LIMITED (IE) | 2019-11-12 | — | — | US | disclosed |
| CN-103012087-B | Green synthetic method of alpha, alpha'-double benzylidene cycloalkanone compound | DALIAN CHEMICAL PHYSICS INST | 2015-02-04 | — | — | CN | disclosed |
| CN-100497293-C | Method of preparing alpha,alpha'-di(substituted benzylidene)cyclone ultraviolet radiation absorbent | UNIV ZHEJIANG (CN) | 2009-06-10 | — | — | CN | disclosed |
| CN-101054348-A | Method of preparing alpha,alpha'-di(substituted benzylidene)cyclone ultraviolet radiation absorbent | UNIV ZHEJIANG (CN) | 2007-10-17 | — | — | CN | disclosed |
| US-6777447-B2 | ANTIINFLAMMATORY AGENTS, BACTERICIDES, OXIDATION RESISTANCE, ANTICANCER AGENTS | GADJAH MADA, FACULTY OF PHARMACY, UNIVERSITY OF, THE (ID) | 2004-08-17 | — | — | US | disclosed |
| US-20030092772-A1 | Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone, and therapeutic uses thereof | GADJAH MADA, FACULTY OF PHARMACY, UNIVERSITY OF, THE (ID) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10471049-B2 | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof | INMT, HNMT, COMT | CYP1A2 1507/4885ALDH1A1 320/4885HTT 30/4885 |
| US-20030092772-A1 | Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone, and therapeutic uses thereof | GSTK1, GSTP1, CAT | CYP1A2 258/4885ALDH1A1 186/4885HTT 1864/4885 |
| US-10576067-B2 | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof | INMT, HNMT, COMT | CYP1A2 1507/4885ALDH1A1 320/4885HTT 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.