SCHEMBL62430

SCHEMBL62430

O=S1(=O)C=Cc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 9/20 0.46
CA1 P00915 7/20 0.46
CA2 P00918 7/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
STAT3 P40763 2/20 0.46
NPC1 O15118 1/20 0.46
MTOR P42345 1/20 0.46
RAB9A P51151 1/20 0.46
HIF1A Q16665 1/20 0.46
GPR3 P46089 1/20 0.39
PLCG2 P16885 1/20 0.37
CA12 O43570 5/20 0.35
NOX1 Q9Y5S8 1/20 0.34
ELANE P08246 1/20 0.31
CA4 P22748 2/20 0.31
CA7 P43166 2/20 0.31
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31003510 1.00 CA9 (0.46) CA9CA1CA2KMT2AMEN1
Water SCHEMBL27659746 0.98 CA9 (0.44) CA9CA1CA2KMT2AMEN1
Methoxymethane SCHEMBL10856175 0.91 CA9 (0.41) CA9CA1CA2KMT2AMEN1
Acetone SCHEMBL8996477 0.88 CA9 (0.39) CA9CA1CA2KMT2AMEN1
Thiophene SCHEMBL28465488 0.88 MEN1 (0.42) CA9CA1CA2KMT2AMEN1
SCHEMBL386507 0.84 GPR3 (0.34) CA9CA1CA2KMT2AMEN1
SCHEMBL19744948 0.82 GPR3 (0.48) CA9CA1CA2KMT2AMEN1
Cyclohexylamine SCHEMBL4918979 0.80 CA1 (0.37) CA9CA1CA2KMT2AMEN1
Valine SCHEMBL11636707 0.77 SLC7A5 (0.44) CA9CA1CA2KMT2AMEN1
Cyclohexane Carboxamide SCHEMBL204775 0.76 SIRT2 (0.38) CA9CA1CA2KMT2APLCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121584026-A Ion polarization enhancement type local high-concentration electrolyte and application thereof in lithium ion battery 国网湖南省电力有限公司 2026-02-27 CN claimed
WO-2025129023-A1 INDOLE AMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS RECTIFY PHARMACEUTICALS, INC. (US) 2025-06-19 WO claimed
CN-116041363-B Benzothiophene sulfone organic crystal, preparation and application as photocatalyst 华中科技大学 2025-02-11 CN claimed
US-20240400591-A1 COMPOUNDS TARGETING MUTANT OF P53 JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-12-05 US claimed
US-20240150508-A1 PHOTO-SWITCHABLE CHEMISTRY FOR REVERSIBLE HYDROGELS AND REUSABLE FLOW CELLS ILLUMINA, INC. (US) 2024-05-09 US claimed
CN-117903781-A Visible light excited organic long afterglow material, three-dimensional structure, preparation method and application thereof 西北工业大学 2024-04-19 CN claimed
WO-2024081563-A1 PHOTO-SWITCHABLE CHEMISTRY FOR REVERSIBLE HYDROGELS AND REUSABLE FLOW CELLS ILLUMINA, INC. (US) 2024-04-18 WO claimed
CN-117552024-A Preparation method of nonmetal-catalyzed 2, 3-dihydrobenzo [ b ] thiophene 1, 1-dioxide 青岛科技大学 2024-02-13 CN claimed
CN-116041366-B Chiral 3-spiro-oxindole benzothiophene sulfone derivative, preparation method and application thereof 成都大学 2023-12-22 CN claimed
CN-117126130-A Method for preparing 2-aryl benzothiophene sulfone by utilizing oxidative Suzuki coupling reaction 浙江师范大学 2023-11-28 CN claimed
CN-1320121-A Substituted 3-cyanoquinolines as protein tyrosine kinase inhibitors AMERICAN CYANAMID CO (US) 2001-10-31 CN claimed
US-6288082-B1 COMPOUNDS SUCH AS 6,7-DIETHOXY-4-(INDAN-5-YLAMINO) -QUINOLINE-3-CARBONITRILE USED AS ANTINEOPLASTIC AGENTS AND IN THE TREATMENT OF POLYCYCSTIC KIDNEY DISEASE AMERICAN CYANAMID COMPANY 2001-09-11 US claimed
EP-1117659-A1 SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS American Cyanamid Company (US) 2001-07-25 EP claimed
EP-1067128-A1 FUSED THIOPHENE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2001-01-10 EP claimed
US-6133279-A A 2,6-DI-T-BUTYLPHENOL DERIVATIVE FOR RENAL DISEASES, E.G., CHRONIC RENAL FAILURE, DIABETIC NEPHROPATHY GLOMERULAR NEPHRITIS, IMMUNOCOMPLEX NEPHRITIS AND ACUTE RENAL FAILURE; CYTOPROTECTIVE AGENT THAT INHIBITS THE LIPID PEROXIDATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-10-17 US claimed
US-6103753-A ADMINISTERING TO A PATIENT FOR INHIBITING THICKENING OF VASCULAR STENOSIS FOLLOWING PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, A 2,6-DI-T-BUTYLPHENOL DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-08-15 US claimed
WO-2000018761-A1 SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS AMERICAN CYANAMID COMPANY (US) 2000-04-06 WO claimed
EP-0950405-A1 REMEDIES FOR RENAL DISEASES AND ORGAN-PRESERVING AGENTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1999-10-20 EP claimed
EP-0868913-A1 INTIMAL THICKENING INHIBITOR Chugai Seiyaku Kabushiki Kaisha (JP) 1998-10-07 EP claimed
US-3960677-A CARBOXY TERMINATED ANIONIC WETTING AGENT, FURAN, THIOPHENE, OR THIAZOLE BRIGHTNER THE HARSHAW CHEMICAL COMPANY (US) 1976-06-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400591-A1 COMPOUNDS TARGETING MUTANT OF P53 TP53, TP53BP1, MDM2 CA9 3658/4885CA1 2782/4885CA2 3601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.