Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891346 | 0.89 | KDM6B (0.67) | KDM6BTSHRADRB3 | |
| SCHEMBL27674847 | 0.87 | PKM (0.60) | ALDH1A1TP53TSHRL3MBTL1POLB | |
| SCHEMBL2033038 | 0.84 | KMT2A (0.55) | KDM6BALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9394713 | 0.83 | ANPEP (0.58) | ANPEPENPEPFOLH1ALDH1A1TP53 | |
| SCHEMBL28335229 | 0.83 | ANPEP (0.58) | ANPEPENPEPFOLH1ALDH1A1TP53 | |
| SCHEMBL3348501 | 0.82 | ALDH1A1 (0.52) | KDM6BALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2033689 | 0.82 | ALDH1A1 (0.52) | KDM6BALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL235131 | 0.81 | KDM6B (0.63) | KDM6BFOLH1POLB | |
| SCHEMBL13925427 | 0.81 | KDM6B (0.58) | KDM6BTSHRADRB3SMN1; SMN2 | |
| SCHEMBL289562 | 0.81 | KDM6B (0.63) | KDM6BFOLH1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903347-B1 | NOVEL CYCLIC DEPSIPEPTIDE PF1022 DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6329338-B1 | CYCLIC OLIGOPEPTIDE TETRAESTES | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0903347-A1 | NOVEL CYCLIC DEPSIPEPTIDE PF1022 DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1999-03-24 | — | — | EP | disclosed |