Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133528 | 0.86 | POLB (0.68) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL29783279 | 0.86 | POLB (0.68) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL19286640 | 0.85 | ALDH1A1 (0.50) | ALDH1A1POLBKDM4ETP53GLA | |
| Hydrochloric Acid SCHEMBL8187825 | 0.85 | POLB (0.66) | ALDH1A1POLBKDM4ETP53GLA | |
| Hydrochloric Acid SCHEMBL7757351 | 0.85 | POLB (0.66) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL6243248 | 0.84 | ALDH1A1 (0.53) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL32691108 | 0.84 | ALDH1A1 (0.53) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL29459236 | 0.84 | ALDH1A1 (0.53) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL3195963 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBKDM4ETP53GLA | |
| SCHEMBL29453019 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBKDM4ETP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252796-B2 | 1-butyl-2-hydroxyaralkyl piperazine derivatives and the uses as anti-depression medicine thereof | CSPC Zhonggi Pharmaceutical Technology (Shijiazhuang) Co. Ltd. (CN) | 2012-08-28 | — | — | US | disclosed |
| US-20110183996-A1 | THE 1-BUTYL-2-HYDROXYARALKYL PIPERAZINE DERIVATIVES AND THE USES AS ANTI-DEPRESSION MEDICINE THEREOF | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2011-07-28 | — | — | US | disclosed |
| US-6864381-B2 | Process for preparing acyloxybenzenesulfonates | CLARIANT GMBH (DE) | 2005-03-08 | — | — | US | disclosed |
| US-6822113-B2 | REACTING ANHYDROUS PHENOLSULFONATES WITH CARBOXYLIC ACID DERIVATIVES BY CONTACTING THE SALT OF A PHENOLSULFONIC ACID AFTER ITS ISOLATION WITH AT LEAST ONE SUBSTANCE HAVING BASIC PROPERTIES; CONTINUOUS PROCESSING; EFFICIENCY; QUALITY | CLARIANT GMBH (DE) | 2004-11-23 | — | — | US | disclosed |
| US-20040198995-A1 | Process for preparing acyloxybenzenesulfonates | CLARIANT GMBH | 2004-10-07 | — | — | US | disclosed |
| US-20040019229-A1 | Process for preparing acyloxybenzenesulfonates | CLARIANT GMBH | 2004-01-29 | — | — | US | disclosed |
| EP-1095127-A1 | NOVEL CYCLIC IMIDO BLEACH ACTIVATORS AND COMPOSITIONS CONTAINING SAME | The Procter & Gamble Company (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002990-A1 | NOVEL CYCLIC IMIDO BLEACH ACTIVATORS AND COMPOSITIONS CONTAINING SAME | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019229-A1 | Process for preparing acyloxybenzenesulfonates | AGPS, ACMSD, ARSA | ALDH1A1 1959/4885POLB 340/4885KDM4E 1998/4885 |
| US-20110183996-A1 | THE 1-BUTYL-2-HYDROXYARALKYL PIPERAZINE DERIVATIVES AND THE USES AS ANTI-DEPRESSION MEDICINE THEREOF | TPH2, TPH1, SLC6A4 | ALDH1A1 290/4885POLB 1351/4885KDM4E 2360/4885 |
| US-20040198995-A1 | Process for preparing acyloxybenzenesulfonates | TST, TYR, ACMSD | ALDH1A1 943/4885POLB 190/4885KDM4E 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.