SCHEMBL624385

SCHEMBL624385

C=CCOC(=O)c1ccc(N(C)C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.56
MAPT P10636 7/20 0.56
HPGD P15428 4/20 0.56
NPC1 O15118 4/20 0.55
KDM4E B2RXH2 4/20 0.55
RAB9A P51151 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
GAA P10253 3/20 0.55
HSD17B10 Q99714 2/20 0.55
MAPK1 P28482 2/20 0.55
TSHR P16473 1/20 0.55
SNCA P37840 1/20 0.54
CYP3A4 P08684 2/20 0.50
LMNA P02545 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
RECQL P46063 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
PRKCA P17252 1/20 0.44
PRKCE Q02156 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29112214 0.88 ALDH1A1 (0.52) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL10086350 0.87 SNCA (0.51) ALDH1A1MAPTHPGDNPC1KDM4E
Hydrochloric Acid SCHEMBL1271593 0.86 SNCA (0.50) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL175786 0.86 SNCA (0.67) ALDH1A1HPGDKDM4EHSD17B10TSHR
SCHEMBL9410231 0.85 SNCA (0.52) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL5494154 0.84 SNCA (0.51) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL5305479 0.84 ALDH1A1 (0.54) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL7715074 0.83 SNCA (0.54) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL5301347 0.82 ALDH1A1 (0.55) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL11637789 0.81 RAB9A (0.57) ALDH1A1MAPTHPGDNPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115903375-A Ecological rotary screen plate-making photosensitive material 上海中大洁润丝实验室科技有限公司 2023-04-04 CN claimed
US-5081278-A PROCESS OF MAKING OPTIONALLY SUBSTITUTED ALKYL P-DIMETHYLAMINOBENZOATES LAMBSON LIMITED (GB) 1992-01-14 US claimed
US-4592906-A Ester of p-dimethylaminocinnamic acid GRAESSER LABORATORIES, LTD. (GB) 1986-06-03 US claimed
EP-0153089-A1 Ultra-violet absorbing compounds and compositions containing said compounds GRAESSER LABORATORIES LIMITED (GB) 1985-08-28 EP claimed
US-4505794-A PHOTOINITIATORS WITH AMINES FOR PHOTOPOLYMERIZATION OF UNSATURATEDCOMPOUNDS; SOLUBILITY CIBA-GEIGY CORPORATION (US) 1985-03-19 US claimed
EP-0005530-B1 NEW MERCAPTOPHENYLKETONES AND THEIR USE AS INITIATORS FOR THE PHOTOPOLYMERISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS CIBA-GEIGY AG (CH) 1982-05-12 EP claimed
JP-61091112-A None JP disclosed
US-20240194422-A1 Encapsulated Supercapacitor Module having a High Voltage and Low Equivalent Series Resistance KYOCERA AVX Components Corporation 2024-06-13 US disclosed
US-11958822-B2 Treprostinil derivative compounds and methods of using same Corsair Pharma, Inc. (US) 2024-04-16 US disclosed
CN-117497335-A Packaged supercapacitor module with high voltage and low equivalent series resistance 京瓷AVX元器件公司 2024-02-02 CN disclosed
US-11875942-B2 Encapsulated supercapacitor module having a high voltage and low equivalent series resistance KYOCERA AVX Components Corporation (US) 2024-01-16 US disclosed
US-20230331691-A1 TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME Corsair Pharma, Inc. 2023-10-19 US disclosed
EP-4238116-A1 SURFACE MOUNTABLE ULTRACAPACITOR DEVICE INCLUDING A RESIN LAYER HAVING VENTS KYOCERA AVX Components Corporation (US) 2023-09-06 EP disclosed
US-4480105-A PHOTOCROSSLINKING POLYMERS CIBA-GEIGY CORPORATION (US) 1984-10-30 US disclosed
US-4459414-A PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1984-07-10 US disclosed
US-4385182-A SENSITIZERS OR PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1983-05-24 US disclosed
US-4363917-A SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS CIBA-GEIGY CORPORATION (US) 1982-12-14 US disclosed
US-4348530-A Thioxanthonecarboxylic acids, esters, thioesters and amides with reactive functional groups CIBA-GEIGY CORPORATION (US) 1982-09-07 US disclosed
US-4279721-A Mercaptophenyl ketones as initiators for the photopolymerization of ethylenically unsaturated compounds CIBA-GEIGY CORPORATION (US) 1981-07-21 US disclosed
US-4078054-A COSMETICS VAN DYK & COMPANY, INCORPORATED (US) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331691-A1 TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME PTGIS, PTGIR, PTGER3 ALDH1A1 1619/4885MAPT 3439/4885HPGD 13/4885
US-11958822-B2 Treprostinil derivative compounds and methods of using same PTGIS, PTGIR, PTGER3 ALDH1A1 1619/4885MAPT 3439/4885HPGD 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.