Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007 | 0.70 | GPR3 (0.54) | LOXL2 | |
| SCHEMBL3483014 | 0.68 | GPR3 (0.31) | — | |
| SCHEMBL8780181 | 0.65 | — | — | |
| SCHEMBL21295788 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL1042069 | 0.64 | GPR3 (0.46) | — | |
| SCHEMBL20553754 | 0.63 | GPR3 (0.35) | LOXL2 | |
| SCHEMBL2057008 | 0.63 | ALDH1A1 (0.40) | — | |
| SCHEMBL10536785 | 0.62 | MAOA (0.38) | — | |
| SCHEMBL21295771 | 0.62 | MAPT (0.36) | — | |
| SCHEMBL21300580 | 0.62 | BCL2L1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019177-A1 | AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| WO-2005019177-A1 | AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |