Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666362 | 0.88 | MEN1 (0.62) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL7730493 | 0.88 | MEN1 (0.62) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL19301024 | 0.88 | MEN1 (0.62) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL21973376 | 0.86 | MEN1 (0.60) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL21973173 | 0.86 | MEN1 (0.60) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL12667478 | 0.86 | MEN1 (0.60) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL13741526 | 0.85 | MEN1 (0.52) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL23515315 | 0.85 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL25735228 | 0.85 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL16705144 | 0.85 | CTSK (0.56) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033129-A1 | ANTIBACTERIAL AMIDE MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2005-04-14 | — | — | WO | disclosed |