Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587166 | 0.81 | GABRA1 (0.48) | GABRA1GABRB1GABRB2LMNACA1 | |
| SCHEMBL27619933 | 0.76 | GABRA1 (0.50) | GABRA1GABRB1GABRB2LMNACA1 | |
| SCHEMBL28412354 | 0.76 | PDE4B (0.46) | GABRA1GABRB1GABRB2LMNACA1 | |
| SCHEMBL8134144 | 0.74 | GABRA1 (0.42) | GABRA1GABRB1GABRB2LMNACA1 | |
| SCHEMBL11968721 | 0.73 | ELANE (0.43) | GABRA1GABRB1GABRB2LMNACA1 | |
| SCHEMBL619043 | 0.72 | GABRA1 (0.61) | GABRA1GABRB1GABRB2LMNACA1 | |
| SCHEMBL16528000 | 0.71 | GABRA1 (0.59) | GABRA1GABRB1GABRB2LMNACA1 | |
| SCHEMBL27705273 | 0.69 | PDE4A (0.41) | GABRA1GABRB1PTGS1PDE4APDE4B | |
| SCHEMBL6237508 | 0.69 | HDAC4 (0.47) | LMNACA1CA2CYP1A2CYP3A4 | |
| SCHEMBL31546110 | 0.69 | PDE4B (0.50) | GABRA1GABRB1GABRB2LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063252-B1 | FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME | OTSUKA KAGAKU KK (JP) | 2005-06-08 | — | — | EP | disclosed |
| US-6632891-B1 | Obtained by an ester exchange reaction between the flame retardant phosphazene and the polycarbonate or polyester resin | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1063252-A1 | FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2000-12-27 | — | — | EP | disclosed |