SCHEMBL619043

SCHEMBL619043

CC(C)c1cccc(-c2ccccc2)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.61
GABRB2 P47870 2/20 0.61
GABRG2 P18507 2/20 0.61
GABRB3 P28472 2/20 0.61
HPGD P15428 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
GABRB1 P18505 2/20 0.61
FAAH O00519 1/20 0.61
LMNA P02545 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
TSHR P16473 1/20 0.61
PTGS1 P23219 1/20 0.61
SLC6A2 P23975 1/20 0.61
HTR2C P28335 1/20 0.61
GABRA5 P31644 1/20 0.61
GABRA3 P34903 1/20 0.61
HTR2B P41595 1/20 0.61
GABRA2 P47869 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10356131 0.92 GABRA1 (0.67) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL15224150 0.86 HNF4A (0.47) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL3806182 0.86 PTPN5 (0.46) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL16528553 0.85 GABRA1 (0.76) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL27619933 0.84 GABRA1 (0.50) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL8594631 0.83 HDAC4 (0.52) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL8780124 0.83 GABRA1 (0.55) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL11314594 0.82 CA1 (0.43) GABRA1GABRB2GABRG2GABRB3HPGD
SCHEMBL146177 0.81 CA1 (0.58) GABRA1GABRB2GABRG2GABRB3HPGD
Benzene SCHEMBL28765069 0.81 CA1 (0.58) GABRA1GABRB2GABRG2GABRB3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11713335-B2 Aminocoumarin compounds and methods of their use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-08-01 US disclosed
EP-2324067-B1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2018-04-25 EP disclosed
US-20160137771-A1 COMPOUND CONTAINING PHENOLIC HYDROXYL GROUP, PHENOLIC RESIN, CURABLE COMPOSITION, CURED PRODUCT THEREOF, SEMICONDUCTOR SEALING MATERIAL, AND PRINTED CIRCUIT BOARD DIC CORPORATION (JP) 2016-05-19 US disclosed
EP-1910427-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2015-05-13 EP disclosed
US-8674026-B2 Ethylene copolymer having multiple pitch in molecular weight distribution and the method of preparing the same SK INNOVATION CO., LTD. (KR) 2014-03-18 US disclosed
EP-2185611-B1 ETHYLENE COPOLYMER HAVING MULTIPLE PITCH IN MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME SK INNOVATION CO LTD (KR) 2013-03-27 EP disclosed
CN-102083870-B Ethylene copolymer and a method of preparing the same SK ENERGY CO LTD 2013-03-06 CN disclosed
CN-101796085-B Ethylene copolymers having multimodal molecular weight distribution and process for their preparation SK ENERGY CO LTD 2012-08-08 CN disclosed
US-20120141702-A1 ETHYLENE COPOLYMER HAVING MULTIPLE PITCH IN MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME SK ENERGY CO., LTD. (KR) 2012-06-07 US disclosed
US-20120041149-A1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK INNOVATION CO., LTD. (KR) 2012-02-16 US disclosed
EP-1336597-B1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL IND (JP) 2008-07-16 EP disclosed
CN-101213217-A Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORP (KR) 2008-07-02 CN disclosed
EP-1910427-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2008-04-16 EP disclosed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 US disclosed
WO-2007040294-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-04-12 WO disclosed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 US disclosed
US-6720460-B2 FORMING HEAT RESISTANT, MECHANICAL STRENGTH POLYMER ADDITIVES; ACID CATALYZED REACTION OF ADAMANTANE DIOL OR TRIOL WITH PHENOLIC DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2004-04-13 US disclosed
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2003-10-02 US disclosed
EP-1336597-A1 Hydroxyphenyl adamantanes and process for the production of the same Honshu Chemical Industry Co., Ltd. (JP) 2003-08-20 EP disclosed
US-3947468-A Production of dibenzopyrans, their isomeric fluorenols and dibenzothiopyrans GENERAL ELECTRIC COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same CYP8B1, DHPS, P4HA1 GABRA1 1504/4885GABRB2 2597/4885GABRG2 3220/4885
US-11713335-B2 Aminocoumarin compounds and methods of their use AAAS, PROC, AADAC GABRA1 3069/4885GABRB2 2632/4885GABRG2 2779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.