Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15088042 | 0.81 | PTGER1 (0.46) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6244123 | 0.79 | HTT (0.55) | MAPTL3MBTL1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6246737 | 0.75 | NPC1 (0.43) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13753876 | 0.75 | MEN1 (0.56) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1178876 | 0.74 | LTA4H (0.58) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3988300 | 0.74 | CCNB2 (0.51) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL11688841 | 0.73 | MEN1 (0.55) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6245259 | 0.73 | MRGPRX4 (0.43) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6243360 | 0.73 | ALDH1A1 (0.53) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10673923 | 0.73 | SMN1; SMN2 (0.47) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033119-A9 | SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS | UNIV WARWICK (GB) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005033119-A1 | SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS | UNIVERSITY OF WARWICK (GB) | 2005-04-14 | — | — | WO | disclosed |