Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243360 | 0.82 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL1577552 | 0.81 | GCK (0.47) | RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL6244123 | 0.80 | HTT (0.55) | SMN1; SMN2LIPEPOLBMAPTMAPK1 | |
| SCHEMBL11785650 | 0.76 | HTT (0.54) | NPC1RAB9ASMN1; SMN2LIPEPOLB | |
| SCHEMBL6245264 | 0.75 | MAPT (0.43) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL6875732 | 0.73 | MAPT (0.50) | SMN1; SMN2LIPEMAPTMAPK1TDP1 | |
| SCHEMBL1178950 | 0.73 | LTA4H (0.60) | NPC1RAB9ALIPEMAPTMAPK1 | |
| SCHEMBL16319383 | 0.73 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL13753876 | 0.73 | MEN1 (0.56) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL6246736 | 0.72 | MRGPRX4 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033119-A9 | SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS | UNIV WARWICK (GB) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005033119-A1 | SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS | UNIVERSITY OF WARWICK (GB) | 2005-04-14 | — | — | WO | disclosed |