Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30270431 | 0.78 | KDM4E (0.59) | FFAR1ALDH1A1HPGDKDM4ECHRM2 | |
| SCHEMBL18952028 | 0.77 | MAPT (0.57) | FFAR1ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL623035 | 0.76 | ADK (0.45) | FFAR1ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL8141107 | 0.75 | ACACB (0.54) | FFAR1FFAR4ACACB | |
| SCHEMBL9328434 | 0.75 | ACACB (0.54) | FFAR1FFAR4ACACB | |
| SCHEMBL9511319 | 0.73 | ACACB (0.53) | FFAR1FFAR4ACACB | |
| SCHEMBL8455468 | 0.73 | FFAR1 (0.68) | FFAR1L3MBTL1CHRM2S1PR1FPR1 | |
| SCHEMBL29856280 | 0.73 | NOS2 (0.44) | ALDH1A1HPGDKDM4EGAANPC1 | |
| SCHEMBL12474028 | 0.72 | MKNK1 (0.51) | ALDH1A1HPGDKDM4EGAAFFAR4 | |
| SCHEMBL2833040 | 0.71 | FFAR1 (0.58) | FFAR1CHRM2S1PR1FPR1FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603513-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020848-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-02-16 | — | — | WO | disclosed |