Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243358 | 0.83 | MRGPRX4 (0.42) | MRGPRX4PPIAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL1178950 | 0.82 | LTA4H (0.60) | LTA4HMAPK14PPIAL3MBTL1ALDH1A1 | |
| SCHEMBL6244117 | 0.81 | MAPT (0.45) | MRGPRX4LTA4HMAPK14PPIAL3MBTL1 | |
| SCHEMBL2645036 | 0.76 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL6245259 | 0.76 | MRGPRX4 (0.43) | MRGPRX4LTA4HMAPK14PPIAL3MBTL1 | |
| SCHEMBL14878215 | 0.75 | MRGPRX4 (0.61) | MRGPRX4L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL28312955 | 0.75 | LTA4H (0.60) | LTA4HMAPK14PPIAL3MBTL1GCK | |
| SCHEMBL20696510 | 0.74 | GCK (0.39) | MRGPRX4PPIAHSD17B10ALDH1A1GCK | |
| SCHEMBL3918355 | 0.74 | APP (0.54) | MRGPRX4L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL6246737 | 0.72 | NPC1 (0.43) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033119-A9 | SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS | UNIV WARWICK (GB) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005033119-A1 | SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS | UNIVERSITY OF WARWICK (GB) | 2005-04-14 | — | — | WO | disclosed |