Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.45 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609987 | 0.92 | FBP1 (0.47) | CASRFBP1PSMB8PSMB5MAPT | |
| Hydrochloric Acid SCHEMBL2283945 | 0.90 | ALDH1A1 (0.52) | CASRFBP1PSMB8PSMB5MAPT | |
| SCHEMBL76778 | 0.88 | ALDH1A1 (0.54) | CASRFBP1PSMB8PSMB5MAPT | |
| SCHEMBL10668295 | 0.86 | ALDH1A1 (0.52) | CASRFBP1PSMB8PSMB5MAPT | |
| SCHEMBL27462536 | 0.85 | FBP1 (0.47) | CASRFBP1PSMB8PSMB5MAPT | |
| Chlorobenzene SCHEMBL28283079 | 0.81 | FBP1 (0.56) | CASRFBP1MAPTTDP1NPC1 | |
| SCHEMBL28283078 | 0.79 | RAB9A (0.51) | CASRFBP1MAPTTDP1NPC1 | |
| SCHEMBL8971386 | 0.74 | SMN1; SMN2 (0.49) | CASRFBP1MAPTTDP1NPC1 | |
| SCHEMBL30066934 | 0.73 | FBP1 (0.40) | CASRFBP1PSMB8PSMB5MAPT | |
| Oxazole SCHEMBL28355211 | 0.73 | NPC1 (0.42) | CASRFBP1PSMB8PSMB5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050287619-A1 | Method and reagent for measuring cholesterol in high-density lipoproteins | KYOWA MEDEX CO., LTD. (JP) | 2005-12-29 | — | — | US | disclosed |
| EP-1555327-A1 | METHOD AND REAGENT FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEINS | Kyowa Medex Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |