Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.52 |
| ▸ | GAK | O14976 | 4/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624827 | 0.79 | MAPT (0.62) | TP53NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1946275 | 0.79 | FYN (0.69) | FYNNPC1MAPTCFTR | |
| SCHEMBL625796 | 0.77 | PIK3CA (0.47) | FYNTP53MAPTLMNAPOLB | |
| SCHEMBL532633 | 0.77 | PIK3CA (0.74) | FYNLMNAPIK3CA | |
| SCHEMBL2255821 | 0.77 | FYN (0.78) | FYNGAKHASPIN | |
| SCHEMBL625391 | 0.76 | HASPIN (0.52) | FYNTP53MAPTLMNAPOLB | |
| SCHEMBL18613295 | 0.75 | FYN (1.00) | FYNPIK3CAGAK | |
| SCHEMBL27794654 | 0.74 | FYN (0.73) | FYNPIK3CA | |
| SCHEMBL15975809 | 0.72 | PIK3CA (0.77) | FYNLMNAPIK3CA | |
| SCHEMBL2255546 | 0.72 | FYN (0.57) | FYNPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |