Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.39 |
| ▸ | FEN1 | P39748 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250190 | 0.83 | PIK3CA (0.45) | TAAR1ESR2FYNPDK2 | |
| SCHEMBL6251135 | 0.83 | RPS6KA3 (0.46) | FYNMEN1MAPTKMT2ACHEK1 | |
| SCHEMBL28874283 | 0.82 | ALDH1A1 (0.45) | ESR2ALOX5APFEN1KDM4EMEN1 | |
| SCHEMBL29281800 | 0.79 | TAAR1 (0.48) | TAAR1ESR2FYNKDM4EMEN1 | |
| SCHEMBL30325664 | 0.76 | TAAR1 (0.59) | TAAR1ESR2FYNKDM4EMEN1 | |
| SCHEMBL27561397 | 0.75 | ESR2 (0.48) | TAAR1ESR2HSD17B1HSD17B2FYN | |
| SCHEMBL5687694 | 0.75 | TAAR1 (0.58) | TAAR1ESR2HSD17B1HSD17B2FYN | |
| SCHEMBL6637403 | 0.74 | TAAR1 (0.47) | TAAR1ESR2HSD17B1HSD17B2FYN | |
| SCHEMBL16428844 | 0.74 | ESR2 (0.55) | TAAR1ESR2HSD17B1HSD17B2FYN | |
| SCHEMBL5843635 | 0.73 | ALOX15 (0.65) | TAAR1ESR2HSD17B1HSD17B2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |