Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572167 | 0.79 | TAAR1 (0.56) | TAAR1ESR2FYNGPR35HSD17B1 | |
| Hydrochloric Acid SCHEMBL6783937 | 0.77 | TAAR1 (0.55) | TAAR1ESR2FYNGPR35HSD17B1 | |
| SCHEMBL16428977 | 0.77 | ESR2 (0.53) | TAAR1ESR2FYNGPR35HSD17B1 | |
| SCHEMBL5687694 | 0.76 | TAAR1 (0.58) | TAAR1ESR2FYNGPR35HSD17B1 | |
| SCHEMBL6573430 | 0.76 | BACE1 (0.58) | ESR2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16428844 | 0.75 | ESR2 (0.55) | TAAR1ESR2FYNGPR35HSD17B1 | |
| SCHEMBL5843635 | 0.74 | ALOX15 (0.65) | TAAR1ESR2FYNHSD17B1HSD17B2 | |
| SCHEMBL6248355 | 0.74 | TAAR1 (0.46) | TAAR1ESR2FYNHSD17B1HSD17B2 | |
| SCHEMBL397893 | 0.73 | ALDH1A1 (0.58) | TAAR1ESR2ALDH1A1MAPTMEN1 | |
| SCHEMBL13092724 | 0.73 | MAPT (0.59) | TAAR1ESR2GPR35HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1418879-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003017955-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-03-06 | — | — | WO | disclosed |