Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ICMT | O60725 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27474313 | 1.00 | CYP1A2 (0.61) | CYP1A2POLBRAB9ALMNAICMT | |
| Phenylhydrazine SCHEMBL11784450 | 0.88 | CYP1A2 (0.49) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL8983732 | 0.87 | CYP1A2 (0.44) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL28877719 | 0.87 | POLB (0.49) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL7584830 | 0.85 | RAB9A (0.47) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL5832438 | 0.85 | POLB (0.46) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL11756536 | 0.84 | CYP1A2 (0.42) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL1399545 | 0.84 | SIRT1 (0.50) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL28857878 | 0.84 | CYP1A2 (0.59) | CYP1A2POLBRAB9ALMNAICMT | |
| SCHEMBL13784467 | 0.84 | POLB (0.46) | CYP1A2POLBRAB9ALMNAICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239111-B1 | DRUG FOR TREATING BRAIN DISEASES, ENABLES PREVENTION OR TREATMENT OF DEMENTIA AND SIMILAR DISEASES CAUSED BY DEGENERATION OR SLOUGHING OF NEURONS, AN ALLY SULFIDE, SULFOXIDE OR SULFONE | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | claimed |
| CN-109476616-B | Piperazinyl methanone NAAA inhibitors | 加利福尼亚大学董事会 | 2023-10-13 | — | — | CN | disclosed |
| CN-110769837-A | Combination cancer immunotherapy with pentaazamacrocycle complexes | 加莱拉实验室有限责任公司 | 2020-02-07 | — | — | CN | disclosed |
| CN-109476616-A | Piperazinyl methanone NAAA inhibitor | 加利福尼亚大学董事会 | 2019-03-15 | — | — | CN | disclosed |
| EP-3006429-B1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-02-06 | — | — | EP | disclosed |
| EP-2655337-B1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-11-23 | — | — | EP | disclosed |
| CN-103261170-B | Fused heterocyclic compounds and their use for pest control | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| EP-3006429-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-9278983-B2 | Fused heterocyclic compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-12-11 | — | — | US | disclosed |
| US-4299762-A | ENZYMATIC DEACYLATION OF ANTIBIOTIC A TO PRODUCE ANTIFUNGAL AGENTS | ELI LILLY AND COMPANY (US) | 1981-11-10 | — | — | US | disclosed |
| US-4297277-A | FUNGICIDES ANTISEPTICS | ELI LILLY AND COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4293486-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293484-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293482-A | PEPTIDE ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293489-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293490-A | PEPTIDE ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4289692-A | CYCLIC PEPTIDE ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0031220-A1 | Derivatives of cyclic peptide nuclei | ELI LILLY AND COMPANY (US) | 1981-07-01 | — | — | EP | disclosed |
| US-4221800-A | ANTIALLERGENS, ANTIHISTAMINES | MILES LABORATORIES, INC. (US) | 1980-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | NR4A1, NR2C2, NR0B1 | CYP1A2 202/4885POLB 4737/4885RAB9A 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.