SCHEMBL6249063

SCHEMBL6249063

C=C(COC(N)=O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.40
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
GRM1 Q13255 1/20 0.38
GRM2 Q14416 1/20 0.38
TET2 Q6N021 5/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
LMNA P02545 3/20 0.33
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HTR1A P08908 1/20 0.33
CHRNB2 P17787 1/20 0.33
CYP2C19 P33261 1/20 0.33
CHRNA7 P36544 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14587468 0.87 ALOX15 (0.46) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL2880121 0.79
SCHEMBL14587467 0.78 ALOX15 (0.39) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL4443594 0.76 CHRM2 (0.40) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL352316 0.75 ALDH1A1 (0.42) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL15926084 0.75 ALDH1A1 (0.41) ALOX15TET2LMNACHRM2CHRM4
SCHEMBL4650431 0.74
SCHEMBL4606403 0.73 HCAR2 (0.41) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL11299148 0.73 ALOX15 (0.56) ALOX15LMNACHRM2CHRM4CHRM5
SCHEMBL246628 0.73 LMNA (0.43) ALOX15GRIK1GRIK2GRM1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP claimed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP claimed
WO-2005047234-A1 METHOD FOR PRODUCING CARBAMATE GROUP-CONTAINING (METH)ACRYLIC ESTERS Röhm GmbH & Co. KG (DE) 2005-05-26 WO disclosed