Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423009 | 0.78 | POLB (0.32) | KDM4ERAB9APOLB | |
| SCHEMBL8290833 | 0.76 | POLB (0.33) | KDM4ENPC1RAB9APOLB | |
| SCHEMBL3876734 | 0.76 | POLB (0.33) | KDM4ENPC1RAB9APOLB | |
| SCHEMBL3876732 | 0.76 | POLB (0.33) | KDM4ENPC1RAB9APOLB | |
| SCHEMBL5775962 | 0.68 | KDM4E (0.37) | KDM4ENPC1RAB9APOLB | |
| SCHEMBL19214808 | 0.66 | TLR8 (0.33) | — | |
| SCHEMBL12261480 | 0.59 | TRPM8 (0.38) | NPC1RAB9A | |
| SCHEMBL1672443 | 0.58 | RAB9A (0.44) | KDM4ENPC1RAB9APOLB | |
| SCHEMBL3881663 | 0.58 | LMNA (0.44) | KDM4ENPC1RAB9APOLB | |
| SCHEMBL5703675 | 0.57 | SCN5A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040142-A9 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMA INC (US) | 2005-06-09 | — | — | WO | disclosed |