Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625069 | 0.88 | ALDH1A1 (0.34) | ALDH1A1LMNATSHR | |
| SCHEMBL7771166 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAADORA3NR1I2PGR | |
| SCHEMBL11932226 | 0.81 | TSHR (0.61) | ALDH1A1LMNAADORA3NR1I2PGR | |
| SCHEMBL15336 | 0.80 | TSHR (0.47) | ALDH1A1LMNATSHRMAPTCYP3A4 | |
| SCHEMBL177731 | 0.80 | TSHR (0.43) | ALDH1A1LMNATSHRMAPTCYP3A4 | |
| SCHEMBL475618 | 0.79 | MGLL (0.61) | ALDH1A1LMNAMGLLCNR1MAPT | |
| SCHEMBL475617 | 0.79 | MGLL (0.61) | ALDH1A1LMNAMGLLCNR1MAPT | |
| SCHEMBL15566 | 0.78 | TSHR (0.50) | ALDH1A1LMNATSHRMAPTCYP3A4 | |
| SCHEMBL20564136 | 0.78 | TSHR (0.50) | ALDH1A1LMNATSHRMAPTCYP3A4 | |
| SCHEMBL15380707 | 0.78 | TSHR (0.50) | ALDH1A1LMNATSHRMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603555-B1 | POLYMER FOAM | TRISTANO PTY LTD (AU) | 2017-02-15 | — | — | EP | claimed |
| US-9255197-B2 | Polymer foam | TRISTANO PTY LTD (AU) | 2016-02-09 | — | — | US | claimed |
| US-20130196103-A1 | POLYMER FOAM | TRISTANO PTY LTD (AU) | 2013-08-01 | — | — | US | claimed |
| EP-2603555-A1 | POLYMER FOAM | Tristano Pty Ltd (AU) | 2013-06-19 | — | — | EP | claimed |
| WO-2012019244-A1 | POLYMER FOAM | TRISTANO PTY LTD (AU) | 2012-02-16 | — | — | WO | claimed |
| CN-106674581-A | Foaming body without residual formamide and preparation method thereof | 良澔科技企业股份有限公司 | 2017-05-17 | — | — | CN | disclosed |
| EP-2603555-B1 | POLYMER FOAM | TRISTANO PTY LTD (AU) | 2017-02-15 | — | — | EP | disclosed |
| US-9255197-B2 | Polymer foam | TRISTANO PTY LTD (AU) | 2016-02-09 | — | — | US | disclosed |
| CN-104080475-A | Deletion mutants of flagellin and methods of use | VAXINNATE CORP | 2014-10-01 | — | — | CN | disclosed |
| US-20130196103-A1 | POLYMER FOAM | TRISTANO PTY LTD (AU) | 2013-08-01 | — | — | US | disclosed |
| EP-2603555-A1 | POLYMER FOAM | Tristano Pty Ltd (AU) | 2013-06-19 | — | — | EP | disclosed |
| CN-102552106-A | Steroid intraocular implants with extended sustained release over 2 months | ALLERGAN INC | 2012-07-11 | — | — | CN | disclosed |
| CN-1972678-B | Steroid intraocular implants with extended sustained release over 2 months | ALLERGAN INC | 2012-02-29 | — | — | CN | disclosed |
| WO-2012019244-A1 | POLYMER FOAM | TRISTANO PTY LTD (AU) | 2012-02-16 | — | — | WO | disclosed |
| CN-101678034-A | Method for treating neovascular ocular diseases | FOVEA PHARMACEUTICALS | 2010-03-24 | — | — | CN | disclosed |
| CN-101448474-A | Compositions and methods for inhibiting adhesions | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-06-03 | — | — | CN | disclosed |
| CN-101437543-A | Combination comprising a VEGF inhibitor and a serine protease for the treatment of neovascular diseases | FOVEA PHARMACEUTICALS SA (FR) | 2009-05-20 | — | — | CN | disclosed |
| CN-1972678-A | Steroid intraocular implants with extended sustained release over 2 months | ALLERGAN INC (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1360497-A | Controlled-release biocompatible ocular drug delivery implant devices and methods | OCULEX PHARM INC (US) | 2002-07-24 | — | — | CN | disclosed |