SCHEMBL6249759

SCHEMBL6249759

C=CC=C1c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.39
CYP11B2 P19099 2/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPK1 P28482 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CES2 O00748 1/20 0.36
APAF1 O14727 1/20 0.36
TERT O14746 1/20 0.36
NPC1 O15118 1/20 0.36
PLIN1 O60240 1/20 0.36
TDP2 O95551 1/20 0.36
S1PR4 O95977 1/20 0.36
LMNA P02545 1/20 0.36
PLA2G1B P04054 1/20 0.36
BCHE P06276 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL878544 1.00 CYP19A1 (0.39) CYP19A1CYP11B2MEN1KMT2AMAPK1
SCHEMBL6724258 0.81 CES1 (0.46) CYP19A1CYP11B2MEN1KMT2AMAPT
SCHEMBL4952565 0.81 MAPK1 (0.41) MEN1KMT2AMAPK1SMN1; SMN2KDM4E
SCHEMBL8676274 0.81 CYP19A1 (0.46) CYP19A1CYP11B2MEN1KMT2AMAPK1
SCHEMBL19067985 0.79 MAPT (0.55) MEN1KMT2AMAPK1MAPTHTT
SCHEMBL13063848 0.75 MAPT (0.44) MEN1KMT2AMAPK1MAPTHTT
SCHEMBL12719742 0.73 S100A4 (0.46) MEN1KMT2AMAPK1MAPTHTT
SCHEMBL9308660 0.73 CYP19A1 (0.41) CYP19A1CYP11B2MEN1KMT2AMAPK1
Propene SCHEMBL3281811 0.71 MEN1 (0.42) CYP19A1CYP11B2MEN1KMT2AMAPK1
SCHEMBL29773476 0.71 MEN1 (0.43) CYP19A1CYP11B2MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110804902-A High-ash corrugated base paper and preparation method thereof 义乌市义南纸业有限公司 2020-02-18 CN claimed
US-6922588-B2 Electrode line BIOTRONIK MESS-UND THERAPIEGERAETE GMBH & CO. (DE) 2005-07-26 US claimed
EP-1354610-B1 Electrode lead made of an intrinsically conductive polymer BIOTRONIK MESS & THERAPIEG (DE) 2005-03-30 EP claimed
US-20040102813-A1 Electrode line BIOTRONIK MESS-UND THERAPIEGERAETE GMBH & CO INGENIEURBUERO BERLIN 2004-05-27 US claimed
CN-112250925-A Phosphorus-containing flame-retardant polybutadiene material and preparation method thereof 邓万菁 2021-01-22 CN disclosed
CN-110804902-A High-ash corrugated base paper and preparation method thereof 义乌市义南纸业有限公司 2020-02-18 CN disclosed
US-6922588-B2 Electrode line BIOTRONIK MESS-UND THERAPIEGERAETE GMBH & CO. (DE) 2005-07-26 US disclosed
US-20040102813-A1 Electrode line BIOTRONIK MESS-UND THERAPIEGERAETE GMBH & CO INGENIEURBUERO BERLIN 2004-05-27 US disclosed