SCHEMBL878544

SCHEMBL878544

C=CC=C1c2ccccc2-c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.39
CYP11B2 P19099 2/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPK1 P28482 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CES2 O00748 1/20 0.36
APAF1 O14727 1/20 0.36
TERT O14746 1/20 0.36
NPC1 O15118 1/20 0.36
PLIN1 O60240 1/20 0.36
TDP2 O95551 1/20 0.36
S1PR4 O95977 1/20 0.36
LMNA P02545 1/20 0.36
PLA2G1B P04054 1/20 0.36
BCHE P06276 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6249759 1.00 CYP19A1 (0.39) CYP19A1CYP11B2MEN1KMT2AMAPK1
SCHEMBL6724258 0.81 CES1 (0.46) CYP19A1CYP11B2MEN1KMT2AMAPT
SCHEMBL4952565 0.81 MAPK1 (0.41) MEN1KMT2AMAPK1SMN1; SMN2KDM4E
SCHEMBL8676274 0.81 CYP19A1 (0.46) CYP19A1CYP11B2MEN1KMT2AMAPK1
SCHEMBL19067985 0.79 MAPT (0.55) MEN1KMT2AMAPK1MAPTHTT
SCHEMBL13063848 0.75 MAPT (0.44) MEN1KMT2AMAPK1MAPTHTT
SCHEMBL12719742 0.73 S100A4 (0.46) MEN1KMT2AMAPK1MAPTHTT
SCHEMBL9308660 0.73 CYP19A1 (0.41) CYP19A1CYP11B2MEN1KMT2AMAPK1
Propene SCHEMBL3281811 0.71 MEN1 (0.42) CYP19A1CYP11B2MEN1KMT2AMAPK1
SCHEMBL29773476 0.71 MEN1 (0.43) CYP19A1CYP11B2MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 US claimed
EP-1475401-B1 Mono-, oligo- and polymers comprising fluorene and aryl groups MERCK PATENT GMBH (DE) 2009-05-27 EP claimed
US-7126013-B2 Mono-, oligo- and polymers comprising fluorene and aryl groups MERCK PATENT GMBH (DE) 2006-10-24 US claimed
EP-1475401-A2 Mono-, oligo- and polymers comprising fluorene and aryl groups MERCK PATENT GmbH (DE) 2004-11-10 EP claimed
US-20040176560-A1 Mono-, Oligo-and polymers comprising fluorene and aryl groups MERCK PATENT GMBH (DE) 2004-09-09 US claimed
EP-1832616-B1 Pi-conjugated polymer RICOH CO LTD (JP) 2012-10-24 EP disclosed
US-20120074336-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) 2012-03-29 US disclosed
US-7973074-B2 π-conjugated mono-, oligo- and polymeric compounds, and photovoltaic cells comprising them COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2011-07-05 US disclosed
US-7964722-B2 Light-driven rotary molecular motors BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-06-21 US disclosed
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS NATIONAL SCIENCE FOUNDATION 2011-03-31 US disclosed
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 US disclosed
JP-2010235610-A MONO-, OLIGO- AND POLYALKYLIDENEFLUORENE AND THEIR USE AS CHARGE TRANSFER MATERIAL MERCK PATENT GMBH 2010-10-21 JP disclosed
EP-1284258-A3 Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GmbH (DE) 2003-06-04 EP disclosed
EP-1284258-A3 Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GmbH (DE) 2003-06-04 EP disclosed
US-20030067267-A1 Mono-, oligo-and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GMBH (DE) 2003-04-10 US disclosed
US-20030067267-A1 Mono-, oligo-and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GMBH (DE) 2003-04-10 US disclosed
US-20030067267-A1 Mono-, oligo-and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GMBH (DE) 2003-04-10 US disclosed
EP-1284258-A2 Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GmbH (DE) 2003-02-19 EP disclosed
EP-1284258-A2 Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GmbH (DE) 2003-02-19 EP disclosed
EP-1284258-A2 Mono-, oligo- and polyalkylidenefluorenes and their use as charge transport materials MERCK PATENT GmbH (DE) 2003-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS CCNA2, CCNO, SCO2 CYP19A1 3455/4885CYP11B2 2330/4885MEN1 4346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.