Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626841 | 0.81 | F2RL3 (0.33) | F2RL3 | |
| SCHEMBL623859 | 0.81 | F2RL3 (0.34) | F2RL3IRAK4TYR | |
| SCHEMBL627112 | 0.80 | F2RL3 (0.34) | F2RL3 | |
| SCHEMBL626163 | 0.79 | HSD11B1 (0.32) | HSD11B1IRAK4 | |
| SCHEMBL625009 | 0.77 | HSD11B1 (0.31) | HSD11B1IRAK4 | |
| SCHEMBL624133 | 0.76 | RORC (0.34) | — | |
| SCHEMBL627850 | 0.76 | JAK1 (0.35) | IRAK4 | |
| SCHEMBL2250793 | 0.66 | DYRK1A (0.32) | IRAK4 | |
| SCHEMBL2257063 | 0.65 | LRRK2 (0.31) | TYR | |
| SCHEMBL626102 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |