Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715556 | 0.87 | CA12 (0.50) | SRCALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL7009014 | 0.87 | CA12 (0.36) | SRCALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL7005305 | 0.87 | ALDH1A1 (0.44) | SRCALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL6862112 | 0.81 | LCK (0.53) | SRCALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8508548 | 0.81 | LCK (0.53) | SRCALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL20162762 | 0.73 | CA12 (0.46) | SRCALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL7008786 | 0.70 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8308145 | 0.69 | HPGD (0.49) | SRCALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL9043080 | 0.67 | KDM4E (0.44) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL7008096 | 0.66 | POLB (0.46) | SRCALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044181-A2 | PROTECTION OF TISSUES AND CELLS FROM CYTOTOXIC EFFECTS OF IONIZING RADIATION BY ABL INHIBITORS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2005-05-19 | — | — | WO | disclosed |