Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HTT | P42858 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248850 | 0.78 | HTT (0.43) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL25927861 | 0.75 | KMT2A (0.57) | PTGS2ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL25928131 | 0.75 | SMN1; SMN2 (0.51) | PTGS2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL11558944 | 0.71 | ALDH1A1 (0.49) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL25928107 | 0.71 | ALDH1A1 (0.41) | PTGS2ALDH1A1HTTLMNAMAPT | |
| SCHEMBL25613746 | 0.70 | GPR3 (0.44) | PTGS2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL14711438 | 0.69 | LPAR1 (0.45) | PTGS2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL4011016 | 0.68 | ALDH1A1 (0.65) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL1562128 | 0.68 | ALDH1A1 (0.57) | ALDH1A1HTTLMNANPSR1HPGD | |
| SCHEMBL30980091 | 0.67 | PTGS2 (0.56) | PTGS2ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |