Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PRNP | P04156 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250314 | 0.86 | KDM4E (0.64) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL8103092 | 0.78 | POLB (0.66) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL317463 | 0.76 | LMNA (0.64) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL437286 | 0.76 | HSD17B10 (0.71) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL1161098 | 0.76 | POLB (0.60) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL31284608 | 0.76 | POLB (0.60) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL29923523 | 0.76 | POLB (0.60) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL1043638 | 0.76 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9732126 | 0.74 | LMNA (0.62) | KDM4EHPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL24915973 | 0.73 | POLB (0.57) | KDM4EHPGDHSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |