Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NQO2 | P16083 | 2/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26400644 | 0.87 | NPSR1 (0.51) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL21173382 | 0.84 | ALDH1A1 (0.62) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL20867790 | 0.80 | NQO1 (0.55) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL12929970 | 0.80 | LMNA (0.58) | KDM4EALDH1A1KMT2APKML3MBTL1 | |
| SCHEMBL8103092 | 0.80 | POLB (0.66) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10199562 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HPGDNQO2MEN1 | |
| SCHEMBL24915721 | 0.79 | KDM4E (0.52) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL24392252 | 0.77 | PDE3B (0.49) | POLBKDM4EALDH1A1NQO2KMT2A | |
| SCHEMBL23683005 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL437286 | 0.77 | HSD17B10 (0.71) | POLBKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | POLB 3227/4885KDM4E 105/4885ALDH1A1 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.