Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | CASP1 | P29466 | 1/20 | 0.71 |
| ▸ | CASP7 | P55210 | 1/20 | 0.71 |
| ▸ | NQO2 | P16083 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GNG2 | P59768 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438970 | 0.86 | NR4A2 (0.60) | HSD17B10ALDH1A1CASP1CASP7NQO2 | |
| SCHEMBL3471999 | 0.83 | ALDH1A1 (1.00) | HSD17B10ALDH1A1CASP1CASP7NQO2 | |
| SCHEMBL8103092 | 0.82 | POLB (0.66) | HSD17B10ALDH1A1NQO2POLBKDM4E | |
| SCHEMBL4748820 | 0.82 | ALDH1A1 (0.66) | HSD17B10ALDH1A1CASP1CASP7NQO2 | |
| SCHEMBL439655 | 0.82 | ALDH1A1 (0.80) | HSD17B10ALDH1A1CASP1CASP7POLB | |
| SCHEMBL27906713 | 0.82 | ALDH1A1 (0.65) | HSD17B10ALDH1A1CASP1CASP7NQO2 | |
| SCHEMBL1289610 | 0.81 | BCHE (0.51) | HSD17B10ALDH1A1CASP1CASP7NQO2 | |
| SCHEMBL27588454 | 0.81 | HSD17B10 (0.49) | HSD17B10ALDH1A1CASP1CASP7NQO2 | |
| SCHEMBL439264 | 0.81 | HSD17B10 (0.64) | HSD17B10ALDH1A1CASP1CASP7NQO2 | |
| SCHEMBL27890180 | 0.80 | ALDH1A1 (0.62) | HSD17B10ALDH1A1CASP1CASP7NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454167-B | Coloring composition, compound, color filter and display device | 住友化学株式会社 | 2023-08-15 | — | — | CN | disclosed |
| CN-114057688-A | Compound and coloring composition | 住友化学株式会社 | 2022-02-18 | — | — | CN | disclosed |
| CN-113454167-A | Coloring composition, compound, color filter and display device | 住友化学株式会社 | 2021-09-28 | — | — | CN | disclosed |
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2016-09-01 | — | — | US | disclosed |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2015-09-24 | — | — | US | disclosed |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2015-09-03 | — | — | US | disclosed |
| US-9049878-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-9000054-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | HSD17B10 3150/4885ALDH1A1 3324/4885CASP1 4658/4885 |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | HSD17B10 3150/4885ALDH1A1 3324/4885CASP1 4658/4885 |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HSD17B10 1094/4885ALDH1A1 664/4885CASP1 2691/4885 |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HSD17B10 1094/4885ALDH1A1 664/4885CASP1 2691/4885 |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HSD17B10 1094/4885ALDH1A1 664/4885CASP1 2691/4885 |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HSD17B10 1094/4885ALDH1A1 664/4885CASP1 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.