SCHEMBL625075

SCHEMBL625075

O=S(=O)(O)c1c(I)ccc2cccc(Nc3ccccc3)c12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.63
TTR P02766 1/20 0.63
CCNA2 P20248 1/20 0.63
CDK2 P24941 1/20 0.63
MAPK14 Q16539 1/20 0.63
NR4A1 P22736 1/20 0.62
FABP1 P07148 1/20 0.56
SNCA P37840 3/20 0.46
CHAT P28329 1/20 0.46
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
CDC25B P30305 1/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 5/20 0.40
KDM4E B2RXH2 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646671 0.86 FABP4 (0.76) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL27945094 0.84 CDK2 (0.65) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL29381891 0.78 FABP4 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL43158 0.78 FABP4 (1.00) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592280 0.77 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL1786500 0.77 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592279 0.77 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL6654772 0.77 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL10353163 0.77 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL31666356 0.75 NR4A1 (0.97) FABP4TTRCCNA2CDK2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583897-B2 Synthetic foldable proteins generated from peptide segments of folding nuclei of reference proteins FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-03-24 US disclosed
US-20230265142-A1 SYNTHETIC FOLDABLE PROTEINS GENERATED FROM PEPTIDE SEGMENTS OF FOLDING NUCLEI OF REFERENCE PROTEINS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-08-24 US disclosed
US-11479590-B2 Synthetic foldable proteins generated from peptide segments of folding nuclei of reference proteins FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-10-25 US disclosed
US-20170362289-A1 SYNTHETIC FOLDABLE PROTEINS GENERATED FROM PEPTIDE SEGMENTS OF FOLDING NUCLEI OF REFERENCE PROTEINS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2017-12-21 US disclosed
EP-2547207-A1 RISPERIDONE IMMUNOASSAY Saladax Biomedical Inc. (US) 2013-01-23 EP disclosed
EP-2544540-A1 LENALIDOMIDE AND THALIDOMIDE IMMUNOASSAYS Saladax Biomedical Inc. (US) 2013-01-16 EP disclosed
WO-2012161938-A1 CLOZAPINE IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2012-11-29 WO disclosed
WO-2012161948-A1 GEMCITABINE IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2012-11-29 WO disclosed
EP-2467139-A1 IMATINIB IMMUNOASSAY Saladax Biomedical Inc. (US) 2012-06-27 EP disclosed
EP-2467400-A1 VARIANT IMMUNOGLOBULINS WITH IMPROVED MANUFACTURABILITY Lonza Biologics plc. (GB) 2012-06-27 EP disclosed
EP-1846763-A2 5-FLUORO-URACIL IMMUNOASSAY Saladax Biomedical Inc. (US) 2007-10-24 EP disclosed
EP-1789791-A2 BUSULFAN IMMUNOASSAY Saladax Biomedical Inc. (US) 2007-05-30 EP disclosed
EP-1774331-A2 CYTOXAN ANTIBODIES AND IMMUNOASSAY Saladax Biomedical Inc. (US) 2007-04-18 EP disclosed
EP-1771732-A2 TAXOL IMMUNOASSAY Saladax Biomedical Inc. (US) 2007-04-11 EP disclosed
WO-2006104970-A1 DOXORUBICIN IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-10-05 WO disclosed
WO-2006102200-A2 DOCETAXEL IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-09-28 WO disclosed
WO-2006086208-A2 5-FLUORO-URACIL IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-08-17 WO disclosed
WO-2006031912-A2 BUSULFAN IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-03-23 WO disclosed
WO-2006020263-A2 CYTOXAN ANTIBODIES AND IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-02-23 WO disclosed
WO-2006015098-A2 TAXOL IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583897-B2 Synthetic foldable proteins generated from peptide segments of folding nuclei of reference proteins MAX, SET, SFPQ FABP4 1236/4885TTR 1623/4885CCNA2 3042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.