Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL9022325 | 0.85 | ALDH1A1 (0.78) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL7259240 | 0.84 | TRPA1 (0.49) | ALDH1A1TSHRMAOBHTTMAPT | |
| Styrene SCHEMBL18245333 | 0.83 | ALDH1A1 (0.82) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL11264130 | 0.83 | ALDH1A1 (0.82) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL2004104 | 0.83 | — | — | |
| Styrene SCHEMBL4986035 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP1A2TP53TDP1 | |
| Styrene SCHEMBL10892600 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP1A2TP53TDP1 | |
| Styrene SCHEMBL6258482 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP1A2TP53TDP1 | |
| Styrene SCHEMBL9776790 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP1A2TP53TDP1 | |
| Styrene SCHEMBL11144289 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP1A2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074179-B1 | Microbicidal active ingredients | CIBA SC HOLDING AG (CH) | 2005-04-20 | — | — | EP | disclosed |
| US-6346260-B1 | HETEROCYCLIC ALKYLENEDIONE PHENOLS AND ALKYLENEDIONE PHENYL PHENOL | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-12 | — | — | US | disclosed |
| EP-1074179-A2 | Microbicidal active ingredients | Ciba SC Holding AG (CH) | 2001-02-07 | — | — | EP | disclosed |