Biphenyl

Biphenyl

SCHEMBL6250985

O=C(O)c1ccccc1-c1ccccc1C(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 3/20 0.63
ALDH1A1 P00352 3/20 0.62
ALOX15 P16050 1/20 0.62
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
ALOX12 P18054 1/20 0.59
CDC25B P30305 1/20 0.57
ATM Q13315 1/20 0.57
FABP3 P05413 1/20 0.57
FABP4 P15090 1/20 0.57
FABP5 Q01469 1/20 0.57
BCAT2 O15382 1/20 0.56
MYC P01106 1/20 0.55
GAA P10253 1/20 0.55
PTPN1 P18031 1/20 0.53
FOLH1 Q04609 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
KDM4E B2RXH2 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL9292498 0.93 HNF4A (0.67) HNF4AALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL36145 0.92 ALDH1A1 (0.72) HNF4AALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL30028907 0.92 ALDH1A1 (0.72) HNF4AALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL2346836 0.91 HNF4A (0.64) HNF4AALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL30578395 0.91 HNF4A (0.64) HNF4AALDH1A1ALOX15CYP3A4CYP2C9
Benzene SCHEMBL28175839 0.91 HNF4A (0.64) HNF4AALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL505412 0.91 HNF4A (0.64) HNF4AALDH1A1ALOX15CDC25BATM
SCHEMBL32677769 0.91 HNF4A (0.64) HNF4AALDH1A1ALOX15CDC25BATM
SCHEMBL32677772 0.91 HNF4A (0.64) HNF4AALDH1A1ALOX15CDC25BATM
SCHEMBL133057 0.90 HNF4A (0.69) HNF4AALDH1A1ALOX15CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646359-B Polycarbonate resin 三菱瓦斯化学株式会社 2023-05-02 CN disclosed
EP-1232058-B1 OPTICAL BODIES MADE WITH A BIREFRINGENT POLYMER 3M INNOVATIVE PROPERTIES CO (US) 2005-08-24 EP disclosed
US-6574045-B2 Optical bodies made with a birefringent polymer 3M INNOVATIVE PROPERTIES COMPANY 2003-06-03 US disclosed
US-6449093-B2 REFLECTIVE INTERFACE 3M INNOVATIVE PROPERTIES COMPANY 2002-09-10 US disclosed
US-20020122252-A1 Optical bodies made with a birefringent polymer 3M INNOVATIVE PROPERTIES COMPANY 2002-09-05 US disclosed
EP-1232058-A1 OPTICAL BODIES MADE WITH A BIREFRINGENT POLYMER 3M Innovative Properties Company (US) 2002-08-21 EP disclosed
US-20020005986-A1 OPTICAL BODIES MADE WITH A BIREFRINGENT POLYMER 3M INNOVATIVE PROPERTIES COMPANY 2002-01-17 US disclosed
WO-2001026891-A1 OPTICAL BODIES MADE WITH A BIREFRINGENT POLYMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-04-19 WO disclosed