SCHEMBL625140

SCHEMBL625140

O=S(=O)(Cl)c1ncc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1796657 0.98 ALDH1A1 (0.36)
SCHEMBL502541 0.80 TXNRD1 (0.44)
Bromide SCHEMBL28322202 0.78 TXNRD1 (0.43)
SCHEMBL329284 0.78
SCHEMBL7423231 0.76
SCHEMBL1259879 0.76
SCHEMBL28510815 0.76
SCHEMBL1727030 0.76
SCHEMBL30821606 0.76 L3MBTL1 (0.38)
SCHEMBL329285 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247357-A Preparation method of minoxidil 吉林大学 2023-12-19 CN claimed
EP-0592438-A1 INDOLE DERIVATIVES. PFIZER (US) 1994-04-20 EP claimed
WO-1992006973-A1 INDOLE DERIVATIVES PFIZER INC. (US) 1992-04-30 WO claimed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 US disclosed
EP-4634186-A1 2,6,9-TRISUBSTITUTED PURINES Astrazeneca AB (SE) 2025-10-22 EP disclosed
US-12441744-B2 2,6,9-trisubstituted purines ASTRAZENECA AB 2025-10-14 US disclosed
US-20250197425-A1 2,6,9-TRISUBSTITUTED PURINES ASTRAZENECA AB (SE) 2025-06-19 US disclosed
US-20240287032-A1 NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF MBD Co., Ltd. (KR) 2024-08-29 US disclosed
US-20240247001-A1 2,6,9-TRISUBSTITUTED PURINES ASTRAZENECA AB (SE) 2024-07-25 US disclosed
WO-2024127350-A1 2,6,9-TRISUBSTITUTED PURINES ASTRAZENECA AB (SE) 2024-06-20 WO disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-5232922-A Cardiovascular disorders HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-03 US disclosed
EP-0240175-B1 INOSOSE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1991-10-16 EP disclosed
EP-0442348-A2 Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-21 EP disclosed
US-4830660-A Imidazolesulfonamide derivatives and herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1989-05-16 US disclosed
US-4824943-A Inosose derivatives and production thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-25 US disclosed
EP-0249938-A2 Imidazolesulfonamide derivatives, herbicides and a method for inhibiting growth of undesirable plants NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-12-23 EP disclosed
EP-0240175-A1 Inosose derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-10-07 EP disclosed
US-4128586-A Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols ALLIED CHEMICAL CORPORATION (US) 1978-12-05 US disclosed
US-3932444-A PLASTICIZERS E. I. DU PONT DE NEMOURS & CO. (US) 1976-01-13 US disclosed