SCHEMBL625141

SCHEMBL625141

c1ccc(N(CC2CO2)CC2CO2)c(Cc2ccccc2N(CC2CO2)CC2CO2)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.34
ALDH1A1 P00352 3/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GLA P06280 1/20 0.33
CTSB P07858 1/20 0.31
DHFR P00374 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
AR P10275 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HSPA5 P11021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29703193 1.00 KDM4E (0.38) KDM4ELMNATDP1USP2ALDH1A1
Glycerin SCHEMBL9580735 0.88 KDM4E (0.33) KDM4ELMNA
SCHEMBL6436617 0.87 KDM4E (0.38) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL31544651 0.87 KDM4E (0.38) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL30015922 0.86 LMNA (0.43) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL6230504 0.86 LMNA (0.43) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL11115495 0.86 CTSB (0.42) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL10413043 0.86 KDM4E (0.37) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL21717710 0.85 KDM4E (0.32) KDM4ELMNATDP1ALDH1A1GLA
SCHEMBL11653549 0.85 KDM4E (0.34) KDM4ELMNAUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11772357-B2 Surface veil and surface film integrated prepreg layer and processes for making the same KORDSA TEKNIK TEKSTIL A.S. (TR) 2023-10-03 US claimed
EP-3593808-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2020-12-09 EP claimed
US-20200339773-A1 SURFACE VEIL AND SURFACE FILM INTEGRATED PREPREG LAYER AND PROCESSES FOR MAKING THE SAME KORDSA TEKNIK TEKSTIL A.S. (TR) 2020-10-29 US claimed
EP-3578185-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2020-08-05 EP claimed
EP-3335785-B1 SELF-HEALING MICROCAPSULES, PROCESS FOR THE PREPARTION THEREOF, POLYMERIC MATRIX AND COMPOSITE MATERIALS COMPRISING THE SAME FUNDACION TECNALIA RES & INNOVATION (ES) 2020-03-25 EP claimed
EP-3452057-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS Tricida Inc. (US) 2019-03-13 EP claimed
WO-2019013716-A1 PRODUCTION METHOD FOR A COMPOSITE MATERIAL MADE OF RESIN FORMULATION-IMPREGNATED FIBER-REINFORCED INTERMEDIATE KORDSA TEKNİK TEKSTİL ANONİM ŞİRKETİ (TR) 2019-01-17 WO claimed
EP-3287133-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION Tricida Inc. (US) 2018-02-28 EP claimed
WO-2017193050-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS TRICIDA, INC. (US) 2017-11-09 WO claimed
EP-2172518-B9 Process for preparing a self-healing composite material LEONARDO SPA (IT) 2017-01-25 EP claimed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US claimed
WO-2007130463-A2 AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS GENZYME CORPORATION (US) 2007-11-15 WO claimed
US-20070244296-A1 Dendritic Polymers with Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-10-18 US claimed
WO-2007009797-A1 AMPHIPHILIC POLYMER COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2007-01-25 WO claimed
US-20010020071-A1 Thermosetting resins CAPOTE MIGUEL ALBERT (US) 2001-09-06 US claimed
EP-0342027-B1 Epoxy-aromatic polysiloxane compositions NAT STARCH CHEM INVEST (US) 1996-01-24 EP claimed
EP-0217657-B1 Low-viscosity epoxy resin, resin composition containing it, and fibre-reinforced composite material containing cured product of the composition SUMITOMO CHEMICAL CO (JP) 1994-04-13 EP claimed
EP-0392348-A2 Toughened thermosetting structural materials CYTEC TECHNOLOGY CORP. (US) 1990-10-17 EP claimed
US-4957995-A Low-viscosity epoxy resin, and fiber-reinforced composite material based on m-alkyl triglycidylaminophenols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-18 US claimed
EP-0148534-B1 BISMALEIMIDES AND PREPREG RESINS THEREFROM AMOCO CORPORATION (US) 1989-03-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 KDM4E 3988/4885LMNA 1465/4885TDP1 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.