SCHEMBL6251442

SCHEMBL6251442

C[Ti](C)(C)C1CCCC2=C1Cc1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.37
CHRM2 P08172 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
DRD1 P21728 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
ADRA1A P35348 1/20 0.37
OPRM1 P35372 1/20 0.37
DRD3 P35462 1/20 0.37
SLC6A3 Q01959 1/20 0.37
KCNH2 Q12809 1/20 0.37
ACHE P22303 2/20 0.33
MAOA P21397 2/20 0.32
SIGMAR1 Q99720 2/20 0.31
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2A6 P11509 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31039630 1.00 CHRM1 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
Hydrochloric Acid SCHEMBL8909535 0.90 CHRM2 (0.32) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL28430120 0.85 CHRM2 (0.34) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL6932058 0.80 CHRM1 (0.39) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL6249924 0.80 SIGMAR1 (0.32) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL31039633 0.80 SIGMAR1 (0.32) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL61050 0.79 CHRM1 (0.38) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL2232626 0.78 CHRM1 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL7641221 0.78 CHRM2 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL7549766 0.77 CHRM1 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115515992-B Olefin polymerization bimetallic activators 陶氏环球技术有限责任公司 2024-08-27 CN disclosed
CN-111433231-B Method for producing styrene resin and styrene resin molded body 出光兴产株式会社 2024-07-16 CN disclosed
CN-111918717-B Olefin polymerization activator 陶氏环球技术有限责任公司 2024-04-09 CN disclosed
CN-113795523-B Olefin functional activators 陶氏环球技术有限责任公司 2024-03-08 CN disclosed
CN-117083307-A Synthesis of sulfonyl halide terminated polyethylene 陶氏环球技术有限责任公司 2023-11-17 CN disclosed
CN-113631585-B Group III anionic complexes of weakly coordinating anions as olefin polymerization catalyst activators 陶氏环球技术有限责任公司 2023-10-20 CN disclosed
CN-116419941-A Preparation of polyolefin-polyacrylate Block copolymer additives for increasing the surface energy of polyethylene 陶氏环球技术有限责任公司 2023-07-11 CN disclosed
CN-116348502-A Preparation of non-polar block copolymers via vinyl terminated polyolefins 陶氏环球技术有限责任公司 2023-06-27 CN disclosed
CN-112074549-B Olefin polymerization activator 陶氏环球技术有限责任公司 2023-06-23 CN disclosed
CN-115515992-A Bimetallic activator for olefin polymerization 陶氏环球技术有限责任公司 2022-12-23 CN disclosed
CN-1323320-A Slurry polymerization process and polymer compositions DOW CHEMICAL CO (US) 2001-11-21 CN disclosed
CN-1317018-A Functionalized catalyst supports and supported catalyst systems DOW CHEMICAL CO (US) 2001-10-10 CN disclosed
US-RE37064-E1 Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 2001-02-20 US disclosed
CN-1255928-A Catalyst system for high yield synthesis of polyolefins DOW CHEMICAL CO (US) 2000-06-07 CN disclosed
US-RE36563-E Transition metal compound, polymerization catalyst using same and process for producing styrenic polymer using said polymerization catalyst IDEMITSU KOSAN CO., LTD. (JP) 2000-02-08 US disclosed
EP-0675139-B1 Process for producing styrenic polymer IDEMITSU KOSAN CO (JP) 1998-10-14 EP disclosed
US-5756612-A COORDINATION CATALYST FOR STYRENE POLYMERIZATION WITH COMPOUNDS OF ALUMINUM, MAGNESIUM AND ZINC IDEMITSU KOSAN CO., LTD. (JP) 1998-05-26 US disclosed
US-5596055-A Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 1997-01-21 US disclosed
EP-0675139-A1 Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 1995-10-04 EP disclosed
EP-0671416-A1 Transition metal compound, polymerization catalyst comprising the same and process for producing styrenic polymer using said polymerization catalyst IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-09-13 EP disclosed