Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 3/20 | 0.43 |
| ▸ | KDM4B | O94953 | 3/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625381 | 0.75 | ADORA3 (0.62) | KDM4AKDM4BKDM5BADORA3ABL1 | |
| SCHEMBL5425263 | 0.71 | GRM1 (0.47) | KDM4AKDM4BKDM5BCSNK2A2CSNK2B | |
| SCHEMBL4656459 | 0.69 | MAPT (0.47) | ADORA3GRM1POLBMAPTL3MBTL1 | |
| SCHEMBL4655569 | 0.69 | GRM1 (0.44) | KDM4AKDM4BKDM5BGRM1MAPT | |
| SCHEMBL4561840 | 0.68 | POLB (0.65) | KDM4EPOLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4715149 | 0.68 | GRM1 (0.45) | KDM4AKDM4BKDM5BGRM1KDM5C | |
| SCHEMBL5429093 | 0.68 | GRM1 (0.40) | ADORA3GRM1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL16151772 | 0.68 | SMN1; SMN2 (0.69) | ABL1EGFRSRCKDM4EL3MBTL1 | |
| SCHEMBL4657866 | 0.67 | GRM1 (0.44) | GRM1GRIA1 | |
| SCHEMBL14962261 | 0.67 | MAPT (0.60) | ADORA3MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |