Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.62 |
| ▸ | KDM4A | O75164 | 3/20 | 0.53 |
| ▸ | KDM4B | O94953 | 3/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625180 | 0.84 | ADORA3 (0.53) | ADORA3KDM4AKDM4BKDM5BAGTR1 | |
| SCHEMBL14962261 | 0.77 | MAPT (0.60) | ADORA3MAPTMEN1HTTKMT2A | |
| SCHEMBL625053 | 0.76 | MEN1 (0.58) | SMN1; SMN2MAPTMEN1HTTKMT2A | |
| SCHEMBL625193 | 0.75 | KDM4A (0.43) | ADORA3KDM4AKDM4BKDM5BCSNK2A2 | |
| SCHEMBL15173923 | 0.74 | ADORA3 (0.61) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL627404 | 0.73 | RAB9A (0.59) | SMN1; SMN2KDM4EMAPTMEN1HTT | |
| SCHEMBL15183181 | 0.73 | ADORA3 (0.72) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL19783013 | 0.73 | ADORA3 (0.78) | ADORA3KDM4AKDM4BKDM5BAGTR1 | |
| SCHEMBL31361544 | 0.72 | ADORA3 (0.77) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL31361489 | 0.72 | ADORA3 (0.76) | ADORA3KDM4AKDM4BKDM5BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |