Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251461 | 0.86 | SMN1; SMN2 (0.40) | MEN1KMT2ACYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL6252887 | 0.80 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL6252198 | 0.69 | MEN1 (0.36) | MEN1KMT2ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL28782326 | 0.65 | CHRM1 (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL279485 | 0.63 | MAPK1 (0.50) | MEN1KMT2ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL13921582 | 0.63 | ALDH1A1 (0.46) | MEN1KMT2ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL18281308 | 0.63 | — | — | |
| SCHEMBL13848563 | 0.63 | MEN1 (0.54) | MEN1KMT2ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL11064976 | 0.62 | ALDH1A1 (0.46) | MEN1KMT2ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL11064973 | 0.62 | ALDH1A1 (0.44) | MEN1KMT2ACYP1A2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243581-B1 | Pyridinium compounds useful for the treatment of AGE-related diseases | TORRENT PHARMACEUTICALS LTD (IN) | 2005-07-13 | — | — | EP | claimed |