SCHEMBL6252887

SCHEMBL6252887

CC(=O)OCCOC(=O)N1C=NC=CC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
PGR P06401 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
HTR1A P08908 1/20 0.34
CHRNB2 P17787 1/20 0.34
TBXA2R P21731 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CHRNA10 Q9GZZ6 1/20 0.34
CHRNA9 Q9UGM1 1/20 0.34
TSHR P16473 1/20 0.34
GALR3 O60755 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252197 0.80 MEN1 (0.36) ALDH1A1CHRM5CHRM1CHRM3PGR
SCHEMBL18281308 0.67
SCHEMBL29446779 0.66 ALDH1A1 (0.65) ALDH1A1CHRM5CHRM1CHRM3PGR
SCHEMBL6252891 0.66 ALDH1A1 (0.34) ALDH1A1CHRM5CHRM1CHRM3PGR
SCHEMBL64593 0.64 ALDH1A1 (0.68) ALDH1A1CHRM5CHRM1CHRM3PGR
Benzene SCHEMBL11159553 0.62 ALDH1A1 (0.59) ALDH1A1CHRM5CHRM1CHRM3PGR
Cyclohexane SCHEMBL8927660 0.62 ALDH1A1 (0.59) ALDH1A1CHRM5CHRM1CHRM3PGR
Ammonia Solution, Strong SCHEMBL5679172 0.61 ALDH1A1 (0.65) ALDH1A1CHRM5CHRM1CHRM3PGR
SCHEMBL19493323 0.60 ALDH1A1 (0.42) ALDH1A1CHRM5CHRM1CHRM3PGR
Methoxymethane SCHEMBL2501432 0.59 ALDH1A1 (0.62) ALDH1A1CHRM5CHRM1CHRM3PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1243581-B1 Pyridinium compounds useful for the treatment of AGE-related diseases TORRENT PHARMACEUTICALS LTD (IN) 2005-07-13 EP claimed