Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453117 | 0.89 | DHFR (0.42) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL20004827 | 0.80 | HSD11B1 (0.41) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL15654560 | 0.79 | MEN1 (0.47) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL27445640 | 0.79 | HSD11B1 (0.41) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL16318984 | 0.79 | HSD11B1 (0.40) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL15102152 | 0.79 | HSD11B1 (0.43) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL29793522 | 0.79 | DHFR (0.44) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL7159270 | 0.79 | HSD11B1 (0.43) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL3451372 | 0.79 | HSD11B1 (0.43) | DHFRHSD11B1NPC1RAB9AKMT2A | |
| SCHEMBL1755976 | 0.77 | HSD11B1 (0.41) | DHFRHSD11B1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058918-A1 | NOVEL PHENYL-BORONIC ACID DERIVATIVES AND METHODS FOR THE PRODUCTION THEREOF | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-30 | — | — | WO | disclosed |